Unfortunately, I cannot answer your question without more context. The questions "What does she do?" and "What is she doing?" both require information about the specific woman you are referring to.
To answer your question effectively, I need some additional details, such as:
Who is "she"? Is she someone you know personally, or someone you saw in a picture or video?
What is the context of the question? Are you trying to learn about her job, her hobbies, or what she is doing at a specific moment in time?
The more information you can provide, the better I will be able to understand your question and give you a helpful answer.